PLOS Computational Biology recently announced that Managing Editor, Gary Beardmore, and Editor in Chief, Jason Papin have collaborated with members of the Center for Reproducible Biomedical Modeling to offer an expert review service which will enable validation of reported results during the peer review process. This service will ensure that results of computational biological models [...]
The Center for Reproducible Biomedical Modeling is excited to announce a new monthly online workshop on modeling software! The goals of the seminar are to foster discussion about challenges associated with stages of the modeling workflow and to provide practical tutorials that address some of these challenges. The workshops will be held at 12 pm [...]
We are now accepting applications for the EBMO Whole-Cell Modeling School which will take place April 7-13, 2019 at the Center for Genomic Regulation in Barcelona, Spain. Whole-cell models that predict phenotype from genotype by representing all of the biochemical activity inside cells are needed to advance biology, bioengineering, and medicine. Achieving whole-cell models will require [...]
We are excited to announce that the NIBIB and NIGMS have committed to fund the center through 2023 to develop technologies for scalable and reproducible modeling, provide free services to the community, advocate for reproducible modeling, and train researchers how to conduct modeling scalably and reproducibly. More info: EurekAlert Icahn School of Medicine [...]
The new website features an overview of the goals, challenges, plans, and methods of whole-cell modeling, as well as links to whole-cell models and whole-cell modeling tools, training materials, events, and research groups.
Jonathan Karr contributed a perspective on modeling and simulating to the standards panel at the 2018 GP-Write meeting.
The Karr Lab joined the GP-Write Standards Working Group and helped write a white paper on the standard protocols and formats that are needed for genome design and writing.
The Karr Lab published a perspective on how researchers are beginning to leverage recent progress in measurement technology, bioinformatics, data sharing, rule-based modeling, and multi-algorithmic simulation to build the first whole-cell models.
The Karr Lab proposed a plan for a project, termed the Human Whole-Cell Modeling Project, to achieve human whole-cell models. The foundations of the plan include technology development, standards development, and interdisciplinary collaboration.
To develop a plan for achieving human whole-cell models, the Karr Lab analyzed the existing models of individual cellular pathways, surveyed the biomodeling community, and reflected on theirr experience developing whole-cell models of bacteria.