Jonathan Karr

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So far Jonathan Karr has created 51 blog entries.

H1 human embryonic stem cell whole-cell model

The H1 human embryonic stem cell (hESC) model is the first step toward whole-cell models of human cells. The model will represent the core cellular functions of all human cells including their metabolism, DNA replication, transcription, translation, protein complexation, RNA and protein degradation, and division. The model focuses on H1-hESCs because ESCs behave as individual [...]

2019-09-17T10:31:43-07:00May 2nd, 2018|Model|

Kinetic Datanator

Kinetic Datanator is a tool for discovering the data needed to build, calibrate, and validate whole-cell models. Kinetic Datanator is composed of an integrated database of experimental data for whole-cell modeling and tools for identifying relevant data for modeling a specific organism and environmental condition. Kinetic Datanator has a web-based graphical interface, a REST [...]

2022-07-26T19:39:31-07:00August 24th, 2017|Software, TR&D 1 - Software|

libRoadRunner

libRoadRunner is a high-performance and portable simulation engine for systems and synthetic biology. It can run on many platforms including Windows, Mac OS, and Linux. libRoadRunner is a major rewrite of the original C# roadRunner developed by Frank Bergmann and Herbert Sauro. The same original functionality however remains, including the original C API, the [...]

2022-07-26T19:41:42-07:00September 12th, 2016|Software, TR&D 3 - Software|
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