The Karr Lab proposed a plan for a project, termed the Human Whole-Cell Modeling Project, to achieve human whole-cell models. The foundations of the plan include technology development, standards development, and interdisciplinary collaboration.
To develop a plan for achieving human whole-cell models, the Karr Lab analyzed the existing models of individual cellular pathways, surveyed the biomodeling community, and reflected on theirr experience developing whole-cell models of bacteria.
Prof. Karr has his team have released an early version of their kinetic_datanator software tool for finding experimental data for building and calibrating dynamical models of cellular biochemistry. kinetic_datanator helps users find data such as metabolite, RNA, and [...]
Profs. Karr and Goldberg are writing a comprehensive primer on whole-cell modeling, both to train their lab and teach the community. It covers the fundamentals of cell modeling, including data aggregation and organization; model design, [...]
Dear colleague, We would like to invite you to participate in a survey of the goals, methods, and challenges of biomodeling. The goal of the survey is to solicit your input into the biomodeling community's [...]