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Combination Therapies for Cancer Treatments - Ideas Lab The National Cancer Institute’s Division of Cancer Biology (NCI DCB) and IBM Research are partnering to build a Community of Accelerated Discovery composed of a multi-disciplinary group of researchers focused on the discovery implications of clinical translation of biologically informed combination therapies for cancer. The over-arching goal [...]

Distribution of knowledge resources of the four element types, obtained from 1,000 BioModels.Only seven most frequently used knowledge resources were specified. Annotations were collected either by thesbotermattribute or thegetAnnotationString()method. In annotation strings, those with eitherbqbiol:isorbqbiol:isVersionOftag were selected. SBO and GO consisted more than 50% of all annotations found. In thefollowing analyses, we used the [...]

Recently published in Current Opinions in Systems Biology: Discrete, logic-based models are increasingly used to describe biological mechanisms. Initially introduced to study gene regulation, these models evolved to cover various molecular mechanisms, such as signaling, transcription factor cooperativity, and even metabolic processes. The abstract nature and amenability of discrete models to robust mathematical analyses make [...]